Our team brings extensive experience from European projects focused on participation in clinical research, and inclusion of underrepresented groups. Notably, in the IHI READI project, we work to increase participation in clinical research among populations that are traditionally underserved and underrepresented. Within READI, we identify barriers and facilitators to engagement and adherence, including logistical constraints (e.g. rural settings, insularity), clinical factors such as multimorbidity, and broader social determinants. We also contribute to the leading the development of best-practice ethical guidelines to ensure fair, inclusive and acceptable implementation of clinical research and interventions targeting these populations.
In addition, our previous work in projects such as Trials@Home, i-CONSENT,PROTECT-EUROPE and BUMPERhas provided us with solid expertise in end-user engagement, behavioural insights, health literacy, decentralised and digital approaches, and the evaluation of their impact on uptake and adherence in real-world settings.