While manufacturing companies place innovation as a top priority to address the environmental crisis, most lack solutions tailored to current and future challenges to be implemented at their facilities. In addition, as innovation in a corporate environment is quickly hampered by the complexity and duration of implementation, innovation is now shifting towards start-ups. This global landscape is also necessary for the SUDOE area, where the capacity for innovation in industrial ecosystems must be improved. To this end, the SCAIRA project aims to develop a personalised training program to support the creation and acceleration of new companies in rural areas for the green transition of the production sector focused on the Aerospace and Automotive sector. Both sectors have a historical anchor in the SUDOE field with a significant number of companies to accompany in their transition. SCAIRAs ambition is to create and attract new economic assets in rural areas while providing innovative responses to industries in green manufacturing and reducing their environmental footprint. SCAIRA will be developed by 5 incubators (2 beneficiaries of research infrastructures) located in rural areas of Portugal, Spain and France, contributing their experience and best practices to the project. Industrial, territorial and environmental challenges will be identified and defined by 5 clusters of partners regional ecosystems. The various clusters, Airbus Atlantic and the industry involved, will complete the program by providing their expertise and knowledge in industrialisation, market analysis, and customer and investor identification. Beyond the project, 45 start-ups will be created and accelerated that will benefit from long-term support through their regional incubator and participation in relevant clusters. The SCAIRA project will restore the attractiveness of the production sector and rural areas, while increasing business culture and labour well-being in the production sector.