The STOP-iatro project brings together a consortium of 6 entities from 3 European countries. The project aims to ensure that professionals involved in care for older patients are aware of the risks associated with iatrogeny (adverse effects associated with care and care on peopleÂ’s health). The objective of the project is to adopt collective strategies to avoid complications associated with care and care that could lead to the loss of autonomy of the elderly, based in particular on the recommendations of the WHO (ICOPE programme). Indeed, the COVID pandemic has particularly affected fragile populations, including the elderly. The negative effects are mainly due to increased barriers to access to essential health services and to the deterioration of the quality of patient care. Despite the existence of national recommendations on the prevention of adverse reactions to care or medicinal products in the territories of the consortium, there has been a clear setback in their implementation. These recommendations, mostly established before the COVID crisis, no longer take into account the current constraints on hospital or primary care actors. Our project is structured around several axes. The first axis aims to identify the obstacles and factors to the implementation of recommendations related to the prevention of iatrogenic dependence, but also to establish a state of knowledge of the professionals identified in the chain. . The second axis is aimed at offering a non-segregated territorial strategy immediately, which breaks down the barriers between city and hospital and is multiprofessional, through innovative methods of collective and social intelligence. The third axis will be to develop training plans on the prevention of iatrogenic dependence. Finally, the fourth axis will allow pilot actions identified jointly by territorial actors for professionals and patients.