Climate change increases hot and dry conditions that boost the increase and intensity of fires in the SUDOE area. The 2022 fires in rural interior areas particularly affected natural parks and protected areas. Being more aggressive fires, the use of fire foams containing flame retardants has increased. These foams contain PFAS (perfluoroalkyl and polyfluoroalkyl substances), highly persistent, mobile and harmful eternal compounds for the environment and health. The degradation of PFAS in soil and water integrates these compounds into the water cycle, causing fluorinated gases that are emitted into the atmosphere, contributing to global warming and climate change. Also, the degradation of gases in the atmosphere causes pollution of water and soil through acid rain, constituting a cycle of environmental pollution. The main objective of ALERT-PFAS is to design and implement a transnational strategy to detect and prevent PFAS pollution in SUDOE natural spaces, as well as to mitigate its effects on ecosystem biodiversity and climate change. The project offers an innovative solution to detect and monitor PFAS in real time and prevent them from forming part of the water cycle, polluting air, soil and water. Pilot actions will be developed in natural parks or protected areas in Portugal, Spain and France, affected by recent fires. Alert-PFAS also aims to train and sensitise all actors in the value chain, including the population. The partnership consists of 10 beneficiaries and 12 associates from the 3 SUDOE countries, who will contribute with their complementary competences. Alert-PFAS will apply innovative technologies such as optical sensors, adsorption and degradation processes, polymeric materials, nanotechnology and AI. The solution, transferable to all SUDOE regions, is aimed at public authorities, natural park managers, water managers, firefighting organisations, civil protection, among others.