The SUDOE is a demographically aged territory that in its interior rural areas presents a situation of increasing depopulation leading to their disappearance. Examples of these territories with low population density are the regions of Castile and Leon (Spain), Beira Baixa (Portugal) and Pays Basque (France). COVID has made clear the health and care gaps for people in these rural settings, especially elderly and dependent people. On the other hand, the difficulty of finding niche markets in which to develop sustainable economic activity, leads young people and highly qualified professionals to leave for cities, further weakening the interior rural environment SUDOE. The common challenge and need of these inland rural areas is to revitalise their economic and social fabric, enhancing employment opportunities that solve societal challenges from the perspective of innovation, combining social needs with development opportunities. Revital seeks to cover the need to provide specialised health care and physical and neurological rehabilitation services (especially to dependents and older people), through technological tools that allow to offer tele-care and tele-rehabilitation services, which will also help to create qualified employment and establish a new population that will energise the rural economy. The project has a clear strategic orientation towards strengthening social cohesion and territorial and demographic balance through social innovation and endogenous development. The challenges and needs to be met are clear: respond to the depopulation and ageing of inland rural areas by establishing a new population with socio-health training, preventing elderly and dependent people from having to migrate to urban areas to access advanced clinical services, as well as developing sustainable production systems based on tele-assistance and tele-rehabilitation technologies, responding to the social needs not sufficiently met in the area of social and health care services.